The raison d'etre of this website is to provide you with hard scientific information which may help you make informed decisions in your quest for health (so far I have blogged concise summaries of over 1,500 scientific studies and have had three books published).

My research is mainly focused on the effects of cholesterol, saturated fat and statin drugs on health. If you know anyone who is worried about their cholesterol levels and heart disease, or has been told to take statin drugs you could send them a link to this website, and to my statin or cholesterol or heart disease books.

David Evans

Independent Health Researcher

Friday, 24 June 2016

Statins significantly reduce dolichol levels

This study was published in BMC Pharmacology and Toxicology 2012, 13(Suppl 1):A51
Study title and authors:
Statins reduce endogenous dolichol levels in the neuroblastoma cell line SH-SY5Y
Bihter Atil, Evelyn Sieczkowski and Martin Hohenegger
Institute of Pharmacology, Center for Physiology and Pharmacology, Medical University Vienna, 1090 Vienna, Austria
This study can be accessed at:

Dolichols play an important role in biosynthesis, protein metabolism, cell vitality and immune system health.

This study assessed the effects of simvastatin on dolichol levels. The laboratory based study used the human SH-SY5Y cells.

The study found that dolichol levels were significantly decreased by simvastatin.

More information about dolichols, statins and the mevalonate pathway:
The deadly effects statins have on the mevalonate pathway
Statin Damage to the Mevalonate Pathway